I wasn't the most talented student in school. I wasn't the brightest. But I was the best. I practiced.
— Preston Burke
Preston Burke
Biographical Information
Full name: Preston Xavier Burke
Status: Alive
Alias: Cardio God
Titles: M.D.
Family Information
Marital: Edra Burke (wife)
Cristina Yang (ex-fiance)
Children: Miscarried with Cristina
Simone Burke
Vivianna Burke
Parents: Jane Burke
Donald Burke
Relatives: Grandmother
Character Information
Profession: Director of Cardiothoracic Surgery
Chief Medical Officer
Head of Cardiothoracic Surgery
Workplace: Klausman Institute for Medical Research
Seattle Grace Hospital
Portrayed by: Isaiah Washington
First Appearance: A Hard Day's Night
Lastest Appearance: We Are Never Ever Getting Back Together
Seasons: 1 2 3 4 10
Preston Burke is a cardiothoracic surgeon. He was formally head of cardio at Seattle Grace Hospital, but quit after leaving his fiancé, Cristina Yang, before their wedding.

Early Life Edit

He grew up in Alabama, where his mother owns a restaurant. He completed his pre-medical studies at Tulane University where he pledged Kappa Alpha Psi and went on the graduate first in his class from Johns Hopkins Medical School.

While in college, he met Erica Hahn, who graduated in second place after him, beginning a rivalry between them.

Season 1 Edit

Burke and Cristina started to date secretly early in her internship.

Season 2 Edit

When he was Mercy West fighting for a heart for Denny, he rushed to the hospital to help Denny right away. Then he got shot in the shoulder before entering the hospital. The wound caused damage to the nerves in his arm.

Season 3 Edit

He was in the mood for a traditional, spirited wedding, which rose conflict with Cristina.

Season 4 Edit

He was one of the 2008 and 2009 applicants for the Harper Avery Award. He was agains many applicants, such as Erica Hahn. He won following his departure from Seattle Grace.

Season 10 Edit

Following his Harper Avery win, he sought out his next challenge. Connecting with a billionaire investor, he founded the Klausman Institute for Medical Research in Zurich, Switzerland with a focus on cardiac research. As its chief medical officer, he managed and worked in the institute for some time until he gave it to Cristina in order for him to move to Milan, Italy at the request of his wife, Edra.

Personality Edit

He is a brilliant surgeon, however he is sometimes over-bearing, especially when it came to his relationship with Cristina. He is extremely neat and organized, especially when it comes to his apartment, which is spotless. He is an excellent cook.

Relationships Edit

Career Edit

Trivia Edit

Notable Episodes Edit

Appearances Edit